Tuesday, October 22, 2013

Brain Tumor Research & Human Cells In Mice

By Robert Sutter


Work in the medical field is going to be done in a number of different ways and typical procedures, at least the first few times around, are done with mice. They are able to react to certain treatments in particular ways, which gives a good idea of how humans are going to react to certain therapies. That being said, how can brain tumor research expand in such a way? It's a point to take into account and a recent story on the matter was successful in grabbing my attention.

A written piece on Science Daily talked about how John Hopkins researchers have brought an FDA-approved drug into effect for treatment of mice. What's interesting in the field of brain tumor research is that these mice had human growth cells inside of them. It's something to make note of, especially when it's been said that after the usage of such a drug, there was no trace of the cells in question. I'd like to think that this could be tremendous for organizations along the lines of Voices against Brain Cancer.

The story spoke about the IDH1 gene in particular, which was expanded upon back in 2008. This particular gene is seen in 70 to 80 percent of tumors and it is oftentimes mutated. One of the things to take into account is that, with said mutation brought into effect, the brain may not be able to put glucose to use, meaning that the energy typically brought from it cannot be utilized. As you can see, there are challenges to be had in this level of research.

Everyone is going to be different in terms of the condition they have, meaning that different methods are going to be set in place. Tumors may be prevalent but the specific types couldn't be more different from one another in terms of how they are structured. Many different components can be brought into account in order to help research along. Knowing that there is a chance for these tumor cells to slow own before ultimately fading away brings a sense of hope to this matter in the medical field.

I believe that there is a great amount of work to be done in the field of brain tumor research and this story is proof of it. I have to believe that this kind of research is one of the most extensive and all you have to do is look at how complicated these growths are to see it. There's a great amount of success to be had with the trial spoke of in this article. I believe that said success can be transitioned into human use but it's going to take some time.




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